Healthcare Technology Letters
Volume 6, Issue 4, August 2019
Volumes & issues:
Volume 6, Issue 4
August 2019
Non-invasive platform to estimate fasting blood glucose levels from salivary electrochemical parameters
- Author(s): Sarul Malik ; Harsh Parikh ; Neil Shah ; Sneh Anand ; Shalini Gupta
- Source: Healthcare Technology Letters, Volume 6, Issue 4, p. 87 –91
- DOI: 10.1049/htl.2018.5081
- Type: Article
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Diabetes is a metabolic disorder that affects more than 400 million people worldwide. Most existing approaches for measuring fasting blood glucose levels (FBGLs) are invasive. This work presents a proof-of-concept study in which saliva is used as a proxy biofluid to estimate FBGL. Saliva collected from 175 volunteers was analysed using portable, handheld sensors to measure its electrochemical properties such as conductivity, redox potential, pH and K+, Na+ and Ca2+ ionic concentrations. These data, along with the person's gender and age, were trained and tested after casewise annotation with their true FBGL values using a set of mathematical algorithms. An accuracy of 87.4 ± 1.7% and a mean relative deviation of 14.1% (R 2 = 0.76) was achieved using a mathematical algorithm. All parameters except the gender were found to play a key role in the FBGL determination process. Finally, the individual electrochemical sensors were integrated into a single platform and interfaced with the authors’ algorithm through a simple graphical user interface. The system was revalidated on 60 new saliva samples and gave an accuracy of 81.67 ± 2.53% (R 2 = 0.71). This study paves the way for rapid, efficient and painless FBGL estimation from saliva.
Computationally efficient mutual authentication protocol for remote infant incubator monitoring system
- Author(s): Subramani Jegadeesan ; Muneeswaran Dhamodaran ; Maria Azees ; Swaminathan Sri Shanmugapriya
- Source: Healthcare Technology Letters, Volume 6, Issue 4, p. 92 –97
- DOI: 10.1049/htl.2018.5006
- Type: Article
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Internet of Things (IoT), cloud computing and wireless medical sensor networks have significantly improved remote healthcare monitoring. In a healthcare monitoring system, many resource-limited sensors are deployed to sense, process and communicate the information. However, continuous and accurate operations of these devices are very important, especially in the infant incubator monitoring system. Because important decisions are made on the received information. Therefore, it is necessary to ensure the authenticity between the incubator monitoring system and doctors. In this work, a public key encryption based computationally efficient mutual authentication protocol is proposed for secure data transmission between incubator monitoring systems and doctors or administrators. The proposed protocol improves performance and reduces the computational cost without compromising the security. The security analysis part shows the strength of the proposed protocol against various attacks, performance analysis part shows that the proposed protocol performs better than other existing protocol based on Rivest–Shamir–Adleman and elliptic-curve cryptography schemes.
Data mining process for predicting diabetes mellitus based model about other chronic diseases: a case study of the northwestern part of Nigeria
- Author(s): Muhammad Musa Uba ; Ren Jiadong ; Muhammad Noman Sohail ; Muhammad Irshad ; Kaifei Yu
- Source: Healthcare Technology Letters, Volume 6, Issue 4, p. 98 –102
- DOI: 10.1049/htl.2018.5111
- Type: Article
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To predict diabetes mellitus model data mining (DM) based approaches on the dataset collected from the seven northwestern states of Nigeria. Data were collected from both primary and secondary sources through questionnaires and verbal interviews from patients with diabetic mellitus and other chronic diseases. Some hospital data were also used from the records of patients involved in this work. The dataset comprises 281 instances with 8 attributes. R programming software (version 5.3.1) was used in the experiments. The DM techniques used in this research were binomial logistic regression, classification, confusion matrix and correlation coefficient. The data were partitioned into training and testing sets. Training data were used in building the model while testing data were used to validate the model. The algorithm for the best-fitted model converges with null deviance: 281.951, residual deviance: 16.476 and AIC: 30.476. The significance variables are AGE, GLU, DBP and KDYP with 0.025, 0.01, 0.05 and 0.025 P values, respectively. The predicted model accounted for the accuracy of ∼97.1%. The correlation analysis results revealed that diabetic patients are more likely to be hypertensive than patients with other chronic diseases considered in the research.
Machine learning approach of automatic identification and counting of blood cells
- Author(s): Mohammad Mahmudul Alam and Mohammad Tariqul Islam
- Source: Healthcare Technology Letters, Volume 6, Issue 4, p. 103 –108
- DOI: 10.1049/htl.2018.5098
- Type: Article
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A complete blood cell count is an important test in medical diagnosis to evaluate overall health condition. Traditionally blood cells are counted manually using haemocytometer along with other laboratory equipment's and chemical compounds, which is a time-consuming and tedious task. In this work, the authors present a machine learning approach for automatic identification and counting of three types of blood cells using ‘you only look once’ (YOLO) object detection and classification algorithm. YOLO framework has been trained with a modified configuration BCCD Dataset of blood smear images to automatically identify and count red blood cells, white blood cells, and platelets. Moreover, this study with other convolutional neural network architectures considering architecture complexity, reported accuracy, and running time with this framework and compare the accuracy of the models for blood cells detection. They also tested the trained model on smear images from a different dataset and found that the learned models are generalised. Overall the computer-aided system of detection and counting enables us to count blood cells from smear images in less than a second, which is useful for practical applications.
Design and evaluation of an alternative wheelchair control system for dexterity disabilities
- Author(s): Samuel Oliver and Asiya Khan
- Source: Healthcare Technology Letters, Volume 6, Issue 4, p. 109 –114
- DOI: 10.1049/htl.2018.5047
- Type: Article
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This work details the design and development of a novel 3D printed, modular alternative wheelchair control system for powered wheelchair users afflicted with dexterity inhibiting disorders, which mechanically interfaces directly with the installed standard joystick. The proposed joystick manipulator utilises an accelerometer for gesture control input processed by the Arduino microprocessor and a mechanical control interface, which sits over a standard installed two-axis proportional joystick, the preferential control system for most powered chair manufacturers. When fitted, this allows powered electric wheelchair users with limited dexterity, independent to navigate their wheelchair unassisted. The mechanical system has been selected so that the joystick manipulator is as universal as possible and can be installed to almost any powered wheelchair that uses a two-axis joystick. The design process and key aspects of the operation of the joystick manipulator are presented as well as field testing on a wheelchair conducted. The test results show that the proposed joystick manipulator is a successful system that can be universally fitted to most powered chairs and offers potentially greater independence for the powered wheelchair user.
Improving the Otsu method for MRA image vessel extraction via resampling and ensemble learning
- Author(s): Yuchou Chang
- Source: Healthcare Technology Letters, Volume 6, Issue 4, p. 115 –120
- DOI: 10.1049/htl.2018.5031
- Type: Article
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Accurate extraction of vessels plays an important role in assisting diagnosis, treatment, and surgical planning. The Otsu method has been used for extracting vessels in medical images. However, blood vessels in magnetic resonance angiography (MRA) image are considered as a sparse distribution. Pixels on vessels in MRA image are considered as an imbalanced data in classification of vessels and non-vessel tissues. To extract vessels accurately, a novel method using resampling technique and ensemble learning is proposed for solving the imbalanced classification problem. Each pixel is sampled multiple times through multiple local patches within the image. Then, vessel or non-vessel tissue is determined by the ensemble voting mechanism via a p-tile algorithm. Experimental results show that the proposed method is able to outperform the traditional Otsu method by extracting vessels in MRA images more accurately.
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