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access icon free Facile nano-free electrochemiluminescence biosensor for detection of sulphamethoxazole via tris(2,2′-bipyridyl)ruthenium(II) and N-methyl pyrrolidone recognition

© The Institution of Engineering and Technology
Received 31/07/2019, Accepted 26/11/2019, Revised 23/10/2019, Published 04/12/2019

The electrochemiluminescence (ECL) system based on the ruthenium complex has become a powerful tool in the field of analytical chemistry. However, the non-aqueous ECL luminescence system, which does not involve complex nano-modification, has not been widely used for the determination of analytes. In this study, N-methyl pyrrolidone was selected as the solvent, and it could also act as a co-reactant of . Based on this, a simple ECL system without nanomaterials was established. Strong ECL was generated. Furthermore, a quenching effect between the excited state of and sulphamethoxazole (SMZ) was observed. Based on this, a sensitive ECL sensor for detecting SMZ is constructed. A linear relationship between ECL signal quenching intensity (ΔI) and the logarithm of SMZ concentration (log C) in the concentration range of 1 × 10−7–1 × 10−5 mol/l is obtained. The limit of detection is as low as 3.33 × 10−9 mol/l. The method has been applied to the detection of SMZ in tap water samples with different concentration levels with satisfactory results, and the recovery was 95.3–102.6%.

Inspec keywords: electrochemical sensors; organic compounds; electrochemistry; electroluminescence; chemiluminescence; biosensors

Other keywords: analyte determination; nonaqueous ECL luminescence system; ECL sensor system; quenching effect; SMZ concentration detection; tris(2,2′-bipyridyl)ruthenium(II); ECL signal quenching intensity; complex nanomodification; nanomaterials; ruthenium complex; nanofree electrochemiluminescence biosensor system; analytical chemistry; sulphamethoxazole detection; N-methyl pyrrolidone recognition

Subjects: Chemical sensors; Biological engineering and techniques; Biosensors; Electrochemistry and electrophoresis; Chemical variables measurement; Biosensors; Chemical sensors

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