http://iet.metastore.ingenta.com
1887

One-pot green synthesis and structural characterisation of silver nanoparticles using aqueous leaves extract of Carissa carandas: antioxidant, anticancer and antibacterial activities

One-pot green synthesis and structural characterisation of silver nanoparticles using aqueous leaves extract of Carissa carandas: antioxidant, anticancer and antibacterial activities

For access to this article, please select a purchase option:

Buy article PDF
$19.95
(plus tax if applicable)
Buy Knowledge Pack
10 articles for $120.00
(plus taxes if applicable)

IET members benefit from discounts to all IET publications and free access to E&T Magazine. If you are an IET member, log in to your account and the discounts will automatically be applied.

Learn more about IET membership 

Recommend Title Publication to library

You must fill out fields marked with: *

Librarian details
Name:*
Email:*
Your details
Name:*
Email:*
Department:*
Why are you recommending this title?
Select reason:
 
 
 
 
 
IET Nanobiotechnology — Recommend this title to your library

Thank you

Your recommendation has been sent to your librarian.

Facile green synthesis of silver nanoparticles (AgNPs) using an aqueous extract of Carissa carandas (C. carandas) leaves was studied. Fabrication of AgNPs was confirmed by the UV–visible spectroscopy which gives absorption maxima at 420 nm. C. carandas leaves are the rich source of the bioactive molecules, acts as a reducing and stabilising agent in AgNPs, confirmed by Fourier transforms infrared spectroscopy. The field emission scanning electron microscope revealed the spherical shape of biosynthesised AgNPs. A distinctive peak of silver at 3 keV was determined by energy dispersive X-ray spectroscopy. X-ray diffraction showed the facecentred cubic structure of biosynthesised AgNPs and thermal stability was confirmed by the thermogravimetric analysis. Total flavonoid and total phenolic contents were evaluated in biosynthesised AgNPs. Biosynthesised AgNPs showed free radical scavenging activities against 2, 2-diphenyl-1-picrylhydrazyl test and ferric reducing antioxidant power assay. In vitro cytotoxicity against hepatic cell lines (HUH-7) and renal cell lines (HEK-293) were also assessed. Finally, biosynthesised AgNPs were scrutinised for their antibacterial activity against methicillin-resistant Staphylococcus aureus, Shigella sonnei, Shigella boydii and Salmonella typhimurium. This study demonstrated the biofabrication of AgNPs by using C. carandas leaves extract and a potential in vitro biological application as antioxidant, anticancer and antibacterial agents.

Inspec keywords: field emission scanning electron microscopy; thermal analysis; nanofabrication; tumours; antibacterial activity; cellular biophysics; nanoparticles; free radical reactions; toxicology; reduction (chemical); nanomedicine; visible spectra; cancer; biomedical materials; microorganisms; Fourier transform infrared spectra; thermal stability; X-ray diffraction; silver; ultraviolet spectra; X-ray chemical analysis

Other keywords: field emission scanning electron microscope; renal cell lines HEK-293; free radical scavenging activities; anticancer activities; thermogravimetric analysis; hepatic cell lines HUH-7; ferric reducing antioxidant power assay; X-ray diffraction; Carissa carandas; methicillin-resistant Staphylococcus aureus; absorption maxima; biofabrication; distinctive peak; Shigella sonnei; total phenolic contents; reducing agent; antibacterial activity; one-pot green synthesis; silver nanoparticles; plant extract colour; face-centred cubic structure; energy dispersive X-ray spectroscopy; UV-visible spectroscopy; aqueous leaves extract; structural characterisation; Ag; antioxidant activities; bioactive molecules; thermal stability; total flavonoid contents; antibacterial activities; stabilising agent; in vitro biological application; 2,2-diphenyl-1-picrylhydrazyl test; Shigella boydii; Salmonella typhimurium; Fourier transforms infrared spectroscopy; in vitro cytotoxicity; spherical shape

Subjects: Structure of solid clusters, nanoparticles, nanotubes and nanostructured materials; Optical properties of metals and metallic alloys (thin films/low-dimensional structures); Electromagnetic radiation spectrometry (chemical analysis); Biomedical materials; Nanotechnology applications in biomedicine; Visible and ultraviolet spectra of metals, semimetals, and alloys; Atom and radical reactions (with themselves or with molecules); Infrared and Raman spectra in metals; Cellular biophysics

References

    1. 1)
      • 1. Lee, H.J., Lee, G., Jang, N.R., et al: ‘Biological synthesis of copper nanoparticles using plant extract’, Une, 2016, 13, p. 15.
    2. 2)
      • 2. Ahmed, S., Ahmad, M., Swami, B.L., et al: ‘A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise’, J. Adv. Res., 2016, 7, pp. 1728.
    3. 3)
      • 3. El-Feky, G.S., Sharaf, S.S., El Shafei, A., et al: ‘Using chitosan nanoparticles as drug carriers for the development of a silver sulfadiazine wound dressing’, Carbohydr. Polym., 2017, 158, pp. 1119.
    4. 4)
      • 4. Bilal, M., Rasheed, T., Iqbal, H.M.N., et al: ‘Silver nanoparticles: biosynthesis and antimicrobial potentialities’, Int. J. Pharmacology, 2017, 13, pp. 832845.
    5. 5)
      • 5. Ahmad, A., Wei, Y., Syed, F., et al: ‘The effects of bacteria-nanoparticles interface on the antibacterial activity of green synthesized silver nanoparticles’, Microb. Pathog., 2017, 102, pp. 133142.
    6. 6)
      • 6. Rasheed, T., Bilal, M., Iqbal, H.M.N., et al: ‘Green biosynthesis of silver nanoparticles using leaves extract of Artemisia vulgaris and their potential biomedical applications’, Colloids Surf. B, Biointerfaces, 2017, 158.
    7. 7)
      • 7. Azizi, M., Ghourchian, H., Yazdian, F., et al: ‘Anti-cancerous effect of albumin coated silver nanoparticles on MDA-MB 231 human breast cancer cell line’, Sci. Rep., 2017, 7, (1), pp. 17.
    8. 8)
      • 8. Ramkumar, V.S., Pugazhendhi, A., Gopalakrishnan, K., et al: ‘Biofabrication and characterization of silver nanoparticles using aqueous extract of seaweed Enteromorpha compressa and its biomedical properties’, Biotechnol. Rep., 2017, 14, pp. 17.
    9. 9)
      • 9. Nayak, D., Minz, A.P., Ashe, S., et al: ‘Synergistic combination of antioxidants, silver nanoparticles and chitosan in a nanoparticle based formulation: characterization and cytotoxic effect on MCF-7 breast cancer cell lines’, J. Colloid Interface Sci., 2016, 470, pp. 142152.
    10. 10)
      • 10. Khatun, M., Habib, M.R., Rabbi, M.A., et al: ‘Antioxidant, cytotoxic and antineoplastic effects of Carissa carandas Linn. Leaves’, Exp. Toxicol. Pathol., 2017, 69, (7), pp. 469476.
    11. 11)
      • 11. Sarma, A., Sarmah, P., Kashyap, D., et al: ‘Antioxidant activity and nutraceutical property of the fruits of an ethno-medicinal plant: Carissa carandas L. found in Brahmaputra valley agro-climatic condition’, J. Pharm. Sci. Res., 2015, 7, (2), pp. 5557.
    12. 12)
      • 12. Azeez, S., Karunakaran, G., Tripathi, P.C., et al: ‘Evaluation of antioxidant activity, total phenolics and phytochemical content of selected varieties of karonda fruits (Carissa carandas)’, Indian J. Agric. Sci., 2016, 86, (6), pp. 815822.
    13. 13)
      • 13. Begum, S., Syed, S.A., Siddiqui, B.S., et al: ‘Carandinol: first isohopane triterpene from the leaves of Carissa carandas L. and its cytotoxicity against cancer cell lines’, Phytochem. Lett., 2013, 6, (1), pp. 9195.
    14. 14)
      • 14. Singh, A., Uppal, G.K.: ‘A review on Carissa carandas – phytochemistry, ethno-pharmacology, and micropropagation as conservation strategy’, Asian J. of Pharm. and Clinical Research, 2015, 8, pp. 2630.
    15. 15)
      • 15. Jeeva, K., Thiyagarajan, M., Elangovan, V., et al: ‘Caesalpinia coriaria leaf extracts mediated biosynthesis of metallic silver nanoparticles and their antibacterial activity against clinically isolated pathogens’, Ind. Crops Prod., 2014, 52, pp. 714720.
    16. 16)
      • 16. Kuppusamy, P., Yusoff, M.M., Maniam, G.P., et al: ‘Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications – an updated report’, Saudi Pharm. J.2016, 24, pp. 473484.
    17. 17)
      • 17. Saeed, N., Khan, M.R., Shabbir, M.: ‘Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L’, BMC Complement. Altern. Med., 2012, 12, (1), p. 1174.
    18. 18)
      • 18. Barku, V.Y.A., Opoku-Boahen, Y., Owusu-Ansah, E., et al: ‘Antioxidant activity and the estimation of total phenolic and flavonoid contents of the root extract of Amaranthus spinosus’, Asian J. Plant Sci. Res., 2013, 3, (1), pp. 6974.
    19. 19)
      • 19. Shekhar, T.C., Anju, G.: ‘Antioxidant activity by DPPH radical scavenging method of Ageratum conyzoides Linn. leaves’, Am. J. Ethnomed., 2014, 1, (4), pp. 244249.
    20. 20)
      • 20. Betancur-Galvis, L., Morales, G., Forero, J., et al: ‘Cytotoxic and antiviral activities of Colombian medicinal plant extracts of the euphorbia genus’, Mem. Inst. Oswaldo Cruz Rio de Janeiro, 2002, 97, (4), pp. 541546.
    21. 21)
      • 21. Krishnaraj, C., Jagan, E.G., Rajasekar, S., et al: ‘Synthesis of silver nanoparticles using Acalypha indica leaf extracts and its antibacterial activity against water borne pathogens’, Colloids Surf. B, Biointerfaces, 2010, 76, (1), pp. 5056.
    22. 22)
      • 22. Yamini, S.G.: ‘Green synthesis of silver nanoparticles from Cleome viscosa: synthesis and antimicrobial activity’. 2011 Int. Conf. on Bioscience, Biochemistry and Bioinformatics, Singapore, 2011, vol. 5, pp. 334337.
    23. 23)
      • 23. Yallappa, S., Manjanna, J., Peethambar, S.K., et al: ‘Green synthesis of silver nanoparticles using Acacia farnesiana (Sweet Acacia) seed extract under microwave irradiation and their biological assessment’, J. Cluster Sci., 2013, 24, (4), pp. 10811092.
    24. 24)
      • 24. Sumi Maria, B., , Devadiga, A., Shetty Kodialbail, V., et al: ‘Synthesis of silver nanoparticles using medicinal Zizyphus xylopyrus bark extract’, Appl. Nanosci., 2015, 5, (6), pp. 755762.
    25. 25)
      • 25. Bhakya, S., Muthukrishnan, S., Sukumaran, M., et al: ‘Biogenic synthesis of silver nanoparticles and their antioxidant and antibacterial activity’, Appl. Nanosci., 2016, 6, (5), pp. 755766.
    26. 26)
      • 26. Paulkumar, K., Gnanajobitha, G., Vanaja, M., et al: ‘Piper nigrum leaf and stem assisted green synthesis of silver nanoparticles and evaluation of its antibacterial activity against agricultural plant pathogens’, Sci. World J., 2014, 2014, Article ID 829894.
    27. 27)
      • 27. MubarakAli, D., Thajuddin, N., Jeganathan, K., et al: ‘Plant extract mediated synthesis of silver and gold nanoparticles and its antibacterial activity against clinically isolated pathogens’, Colloids Surf. B, Biointerfaces, 2011, 85, (2), pp. 360365.
    28. 28)
      • 28. Raja, S., Ramesh, V., Thivaharan, V.: ‘Green biosynthesis of silver nanoparticles using Calliandra haematocephala leaf extract, their antibacterial activity and hydrogen peroxide sensing capability’, Arab. J. Chem., 2017, 10, (2), pp. 253261.
    29. 29)
      • 29. Bankar, A., Joshi, B., Kumar, A.R., et al: ‘Banana peel extract mediated novel route for the synthesis of silver nanoparticles’, Colloids Surf. A, Physicochem. Eng. Aspects, 2010, 368, (1-3), pp. 5863.
    30. 30)
      • 30. Ahmad, N., Sharma, S.: ‘Green synthesis of silver nanoparticles using extracts of Ananas comosus’, Green Sustain. Chem., 2012, 2, pp. 141147.
    31. 31)
      • 31. Zia, F., Ghafoor, N., Iqbal, M., et al: ‘Green synthesis and characterization of silver nanoparticles using Cydonia oblong seed extract’, Appl. Nanosci., 2016, 6, (7), pp. 10231029.
    32. 32)
      • 32. Khan, M.A.M., Kumar, S., Ahamed, M., et al: ‘Structural and thermal studies of silver nanoparticles and electrical transport study of their thin films’, Nanoscale Res. Lett., 2011, 6, pp. 18.
    33. 33)
      • 33. Carvalho, E.A., Freitas, A.M., Silva, G.H., et al: ‘Thermal and structural analysis of germinate glass and thin films co-doped with silver nanoparticles and rare earth ions with insights from visible and Raman spectroscopy’, Vib. Spectrosc., 2016, 87, pp. 143148.
    34. 34)
      • 34. Basu, S., Maji, P., Ganguly, J.: ‘Rapid green synthesis of silver nanoparticles by aqueous extract of seeds of Nyctanthes arbor-tristis’, Appl. Nanosci., 2016, 6, (1), pp. 15.
    35. 35)
      • 35. Perugu, S., Nagati, V., Bhanoori, M.: ‘Green synthesis of silver nanoparticles using leaf extract of medicinally potent plant Saraca indica: a novel study’, Appl. Nanosci., 2016, 6, (5), pp. 747753.
    36. 36)
      • 36. Dipankar, C., Murugan, S.: ‘The green synthesis, characterization and evaluation of the biological activities of silver nanoparticles synthesized from Iresine herbstii leaf aqueous extracts’, Colloids Surf. B, Biointerfaces, 2012, 98, pp. 112119.
    37. 37)
      • 37. Ingle, A., Rai, M., Gade, A., et al: ‘Fusarium solani: a novel biological agent for the extracellular synthesis of silver nanoparticles’, J. Nanoparticle Res., 2009, 11, (8), pp. 20792085.
    38. 38)
      • 38. Moteriya, P., Padalia, H., Chanda, S.: ‘Characterization, synergistic antibacterial and free radical scavenging efficacy of silver nanoparticles synthesized using Cassia roxburghii leaf extract’, J. Genet. Eng. Biotechnol., 2017, 15, (2), pp. 505513.
    39. 39)
      • 39. Li, Y., Ma, D., Sun, D., et al: ‘Total phenolic, flavonoid content, and antioxidant activity of flour, noodles, and steamed bread made from different colored wheat grains by three milling methods’, Crop J., 2015, 3, (4), pp. 328334.
    40. 40)
      • 40. Sharma, O.P., Bhat, T.K.: ‘DPPH antioxidant assay revisited’, Food Chem., 2009, 113, (4), pp. 12021205.
    41. 41)
      • 41. Xie, J., Schaich, K.M.: ‘Re-evaluation of the 2,2-diphenyl-1-picrylhydrazyl free radical (DPPH) assay for antioxidant activity’, J. Agric. Food Chem., 2014, 62, (19), pp. 42514260.
    42. 42)
      • 42. Benzie, I.F.F., Strain, J.J.: ‘The ferric reducing ability of plasma (FRAP) as a measure of ‘antioxidant power’: the FRAP assay’, Anal. Biochem., 1996, 239, (1), pp. 7076.
    43. 43)
      • 43. Mahendran, G., Ranjitha Kumari, B.D.: ‘Biological activities of silver nanoparticles from Nothapodytes nimmoniana (Graham) Mabb. fruit extracts’, Food Sci. Human Wellness, 2016, 5, (4), pp. 207218.
    44. 44)
      • 44. Kim, S., Choi, I.H.: ‘Phagocytosis and endocytosis of silver nanoparticles induce interleukin-8 production in human macrophages’, Yonsei Med. J., 2012, 53, (3), pp. 654657.
    45. 45)
      • 45. Piao, M.J., Kang, K.A., Lee, I.K., et al: ‘Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis’, Toxicol. Lett., 2011, 201, (1), pp. 92100.
    46. 46)
      • 46. Bilal, M., Rasheed, T., Iqbal, H.M.N., et al: ‘Development of silver nanoparticles loaded chitosan-alginate constructs with biomedical potentialities’, Int. J. Biol. Macromol., 2017, 105, pp. 393400.
    47. 47)
      • 47. Marambio-Jones, C., Hoek, E.M. V.: ‘A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment’, J. Nanoparticle Res., 2010, 12, (5), pp. 15311551.
    48. 48)
      • 48. Umashankari, J., Inbakandan, D., Ajithkumar, T.T., et al: ‘Mangrove plant, Rhizophora mucronata (Lamk, 1804) mediated one pot green synthesis of silver nanoparticles and its antibacterial activity against aquatic pathogens’, Aquat. Biosyst., 2012, 8, (1), p. 11.
    49. 49)
      • 49. Patra, J.K., Baek, K.H.: ‘Antibacterial activity and synergistic antibacterial potential of biosynthesized silver nanoparticles against foodborne pathogenic bacteria along with its anticandidal and antioxidant effects’, Front. Microbiol., 2017, 8, pp. 167176.
    50. 50)
      • 50. Patra, J.K., Das, G., Baek, K.H.: ‘Phyto-mediated biosynthesis of silver nanoparticles using the rind extract of watermelon (Citrullus lanatus) under photo-catalyzed condition and investigation of its antibacterial, anticandidal and antioxidant efficacy’, J. Photochem. Photobiol. B, Biol., 2016, 161, pp. 200210.
http://iet.metastore.ingenta.com/content/journals/10.1049/iet-nbt.2017.0261
Loading

Related content

content/journals/10.1049/iet-nbt.2017.0261
pub_keyword,iet_inspecKeyword,pub_concept
6
6
Loading
This is a required field
Please enter a valid email address