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access icon free Antioxidant and antibacterial activity evaluation of 3-hydroxybenzaldehyde: the product of thymol oxidation by a new magnetic nanocatalyst

© The Institution of Engineering and Technology
Received 08/06/2016, Accepted 27/01/2017, Revised 18/01/2017, Published 27/01/2017

In this study maghemite nanoparticles were synthesised, they were first coated by sodium alginate and then by chitosan. Then acetanilide was introduced to maghemite nanoparticles that were coated by alginate and chitosan. Finally a silver complex was made with acetanilide and the magnetic nanocatalyst was synthesised. This nanocatalyst was used for the oxidation of thymol, then antioxidant and antibacterial properties of the oxidation product were assessed. Characterisation of this nanocatalyst was performed by Fourier transform infrared spectroscopy (FT-IR), X-ray diffractometer, scanning electron microscope (SEM) and value stream mapping. Creation of the product was confirmed by FT-IR and gas chromatography-mass spectroscopy. According to SEM, the size of the nanocatalyst was in the range of 46–70 nm. 3-hydroxybenzaldehyde was obtained from the oxidation of thymol. It had antioxidant property as evident from Di (phenyl) – (2, 4, 6-trinitrophenyl) iminoazanium and the Folin–Ciocalteu method. Diffusion and dilution methods were used for the evaluation of the antibacterial activity. It was obvious from MIC that gram negative strains were more resistant than gram positive ones, and from minimum bactericidal concentration, it was obvious that Escherichia coli was the most resistant gram negative strain, and Bacillus subtilis was the most resistant gram positive strain.

Inspec keywords: microorganisms; X-ray diffraction; nanoparticles; magnetic particles; diffusion; oxidation; Fourier transform infrared spectra; nanomagnetics; mass spectroscopic chemical analysis; antibacterial activity; organic compounds; iron compounds; nanofabrication; scanning electron microscopy; catalysts; chromatography

Other keywords: diffusion; dilution; FTIR; antioxidant properties; magnetic nanocatalyst; Folin–Ciocalteu method; X-ray diffractometer; sodium alginate; chitosan; value stream mapping; Fourier transform infrared spectroscopy; Escherichia coli; Fe2O3; antibacterial activity; scanning electron microscope; Bacillus subtilis; gram positive strain; 3-hydroxybenzaldehyde; maghemite nanoparticles; acetanilide; gram negative strains; thymol oxidation; gas chromatography-mass spectroscopy

Subjects: Heterogeneous catalysis at surfaces and other surface reactions; Chromatography; Mass spectrometry (chemical analysis); Optical properties of other inorganic semiconductors and insulators (thin films, low-dimensional and nanoscale structures); Fine-particle magnetic systems; Infrared and Raman spectra in inorganic crystals; Biomedical materials; Magnetic properties of nanostructures; Other methods of nanofabrication

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