access icon free Computational study on focused microwave thermotherapy for knee pathological treatment

This study is a computational study on focused microwave thermotherapy for knee pathological treatment using the time reversal (TR) principle in musculoskeletal disorders. The authors presented a modified TR algorithm with amplitude compensation for an accurate beam focusing of the knee tumour location in a lossy medium. Furthermore, they proposed a new approach called the truncated threshold method, which could be used to apply an effective beam focusing on a tumour location in the knee while the unwanted hot spots are controlled in the normal tissue region. Compared to the other existing methods, this new approach has the advantages of being implemented simply in the unwanted hot spot control and having a similar performance to the beam focusing on the target location. The application of the proposed algorithm and the new hot spot control method to knee pathological tissue achieved acceptable electromagnetic (EM) and thermal results. The anatomical based two-dimensional (2D) knee model for the simulation analysis was implemented using a segmentation result of the Korean human body model obtained from magnetic resonance imaging. 2D finite-difference time-domain electromagnetic and thermal solvers were developed and applied to conduct the 915 MHz focused microwave thermotherapy for knee pathological treatment.

Inspec keywords: biomedical MRI; image segmentation; finite difference time-domain analysis; tumours; medical disorders; medical image processing; patient treatment; biological tissues; compensation

Other keywords: frequency 915 MHz; Korean human body model; tumour location; knee pathological treatment; knee pathological tissue; time reversal principle; 2D finite-difference time-domain electromagnetic solvers; amplitude compensation; truncated threshold method; modified TR algorithm; magnetic resonance imaging; knee tumour location; thermal solvers; normal tissue region; 2D knee model; anatomical based two-dimensional knee model; computational study; musculoskeletal disorders; lossy medium; focused microwave thermotherapy; temperature 43 degC; simulation analysis; beam focusing; hot spot control method

Subjects: Other numerical methods; Biomedical magnetic resonance imaging and spectroscopy; Numerical approximation and analysis; Patient diagnostic methods and instrumentation; Optical, image and video signal processing; Other numerical methods; Biology and medical computing; Computer vision and image processing techniques; Medical magnetic resonance imaging and spectroscopy

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