A highly sensitive, rapid and convenient biosensor based on film bulk acoustic resonator has been developed for detection of pesticide residues in agricultural products. When the pesticide molecules are bound to the immobilised antibodies on the resonator sensing surface, the resonant frequency is obviously reduced because of additional mass. Trace pesticide in the solutions was detected through real-time monitoring of the resonant frequency during antigen–antibody reactions on the resonator surface. Using the proposed biosensor, realised is a convenient and rapid detection process (less than 1 min) and a remarkable low detection limit (ppb level) for the pesticide. On the basis of the sensing performances, the film bulk acoustic resonator shows promising applications for food safety guarantees.

References

1. 1)
  - 3. Van Dyk, J.S., Pletschke, B.: ‘Review on the use of enzymes for the detection of organochlorine, organophosphate and carbamate pesticides in the environment’, Chemosphere, 2011, 82, (3), pp. 291–307 (doi: 10.1016/j.chemosphere.2010.10.033).
2. 2)
  - 8. Chen, D., Wang, J., Xu, Y., Li, D., Zhang, L., Li, Z.: ‘Highly sensitive detection of organophosphorus pesticides by acetylcholinesterase-coated thin film bulk acoustic resonator mass-loading sensor’, Biosens. Bioelectron., 2013, 41, (1), pp. 163–167 (doi: 10.1016/j.bios.2012.08.018).
3. 3)
  - 1. Erbahar, D.D., Gurol, I., Gumus, G., Musluoglu, E., Ozturk, Z.Z., Ahsen, V., Harbeck, M.: ‘Pesticide sensing in water with phthalocyanine based QCM sensors’, Sens. Actuators B, Chem., 2012, 173, pp. 562–568 (doi: 10.1016/j.snb.2012.07.041).
4. 4)
  - 4. Periasamy, A.P., Umasankar, Y., Chen, S.M.: ‘Nanomaterials – acetylcholinesterase enzyme matrices for organophosphorus pesticides electrochemical sensors: a review’, Sensors, 2009, 9, (6), pp. 4034–4055 (doi: 10.3390/s90604034).
5. 5)
  - 6. Chen, D., Xu, Y., Wang, J., Zhang, L.: ‘Nerve gas sensor using film bulk acoustic resonator modified with a self-assembled Cu2 + /11-mercaptoundecanoic acidbilayer’, Sensor. Actuators B, 2010, 150, pp. 483–486 (doi: 10.1016/j.snb.2010.07.047).
6. 6)
  - 2. Arlett, J.L., Myers, E.B., Roukes, M.L.: ‘Comparative advantages of mechanical biosensors’, Nat. Nanotechnol., 2011, 6, (4), pp. 203–215 (doi: 10.1038/nnano.2011.44).
7. 7)
  - 9. Chen, D., Wang, J.J., Liu, Q.X., Xu, Y., Li, D.H., Liu, Y.J.: ‘Highly sensitive ZnO thin film bulk acoustic resonator for hydrogen detection’, J. Micromech . Microeng., 2011, 21, (11), pp. 1150181–1150187 (doi: 10.1088/0960-1317/21/11/115018).
8. 8)
  - 5. Alvarez, M., Calle, A., Tamayo, J., Lechuga, L.M., Abad, A., Montoya, A.: ‘Development of nanomechanical biosensors for detection of the pesticide DDT’, Biosens. Bioelectron., 2003, 18, (5–6), pp. 649–653 (doi: 10.1016/S0956-5663(03)00035-6).
9. 9)
  - 7. Qiu, X., Zhu, J., Oiler, J., Yu, C., Wang, Z., Yu, H.: ‘Film bulk acoustic-wave resonator based ultraviolet sensor’, Appl. Phys. Lett., 2009, 94, (15), pp. 151917–0 (doi: 10.1063/1.3122342).

Correspondence

This article has following corresponding article(s):

in brief

Film bulk acoustic biosensor for detection of trace pesticide residues in agricultural products

References

Related content