Velocity measurement is a basic task of radars. The target velocity is usually estimated according to the Doppler frequency shift. While traditional Doppler methods are unsuitable for high-speed targets, since the serious range migration between adjacent echoes causes phase wrapping. The serious range migration also interferes the coherent integration to improve the accuracy of the velocity estimation. A velocity measurement method based on Keystone transform using entropy minimization is studied to solve this problem. This method applies Keystone transform to the echo to calculate the ambiguity degree with the help of entropy minimization. The proposed algorithm estimates the ambiguity degree with no error at a wider range of SNR than the traditional method. The ambiguous Doppler frequency is obtained according to the slow time. Theoretical analyses and simulations show that this method has very high precision.