This paper describes a 0.35 μm CMOS A/D interface for automotive sensor applications. The circuit is made up of a low-noise instrumentation preamplifier and a chopper-stabilized switched-capacitor 2-1 cascade ΣΔ modulator. The preamplifier has a fixed gain of 10 and it is capable of handling signals with 20 kHz-bandwidth and amplitudes ranging from μVs to hundreds of mVs with a signal-to-(noise+distortion) ratio over 100 dB. The modulator can be digitally programmed to yield four gain values (×0.5, ×1, ×2 and ×4) and incorporates several design-for-testability strategies. Both circuits have been designed to operate within the stringent environmental conditions of automotive electronics (-40 °C, 175 °C). The modulator is clocked at 5.12 MHz and consumes 14.7 mW from a single 3.3-V supply. Experimental results show an overall dynamic range of 110 dB within a 20-kHz signal bandwidth and 113 dB for 10-kHz signals. These performance features place the reported circuit at the edge of the state-of-the-art high-resolution ΣΔ modulators.