Due to the shortcoming of being cracked easily of single chaotic map, a novel hybrid chaotic sequence is proposed. The model of this hybrid chaotic sequence is based on combining two chaotic maps and changing the parameter of the one chaotic map. The balance, randomness and correlation property of the hybrid chaotic sequence are analyzed. And a model of spread spectrum communication system is established, in which the hybrid chaotic sequence is used as the spread spectrum sequence. The result of the simulation shows that the hybrid chaotic sequence which with well balance, better randomness and excellent correlation property can be applied as the spread spectrum sequence.