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Experimental investigation of thermal conductivity of medical nanofluids based on functionalised single-wall carbon nanotube and conjugated cisplatin

Experimental investigation of thermal conductivity of medical nanofluids based on functionalised single-wall carbon nanotube and conjugated cisplatin

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Thermal engineering parameters such as thermal conductivity (TC) can play an important role in developing medical nanofluids with improved stability and better drug release. In this reported work, an engineering perspective is strategised for the development of medical nanofluids containing functionalised single-wall carbon nanotubes and conjugated cisplatin. These nanofluids were developed by two biocompatible phospholipids. For the first time, the change in TC values of this medical nanofluid was investigated. The change in the drug release was examined before and after dialysis with change in pH and temperature, in vitro. It was found that an increase in temperature leads to higher TC and a decrease in pH provides better thermophysical conditions for the drug release. These findings strongly suggest that TC could be an important parameter in the development of medical nanofluids for cancer treatment.

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