Interactions of electrical fields with fluids:laboratory-on-a-chip applications
Interactions of electrical fields with fluids:laboratory-on-a-chip applications
- Author(s): J. Wu
- DOI: 10.1049/iet-nbt:20070023
For access to this article, please select a purchase option:
Buy article PDF
Buy Knowledge Pack
IET members benefit from discounts to all IET publications and free access to E&T Magazine. If you are an IET member, log in to your account and the discounts will automatically be applied.
Thank you
Your recommendation has been sent to your librarian.
- Author(s): J. Wu 1
-
-
View affiliations
-
Affiliations:
1: Department of Electrical and Computer Engineering, University of Tennessee, Knoxville, USA
-
Affiliations:
1: Department of Electrical and Computer Engineering, University of Tennessee, Knoxville, USA
- Source:
Volume 2, Issue 1,
March 2008,
p.
14 – 27
DOI: 10.1049/iet-nbt:20070023 , Print ISSN 1751-8741, Online ISSN 1751-875X
- « Previous Article
- Table of contents
- Next Article »
The area of ‘laboratory-on-a-chip’, miniaturised or microfluidic analysis systems, is a rapidly developing field. At the microscale, electrokinetic processes become enhanced, and the advent of AC electrokinetics (EK) in recent years further promotes the development of electrokinetic devices for microfluidics. ACEK has demonstrated to manipulate fluids and polarisable particles at low voltages without some of the disadvantages from DCEK, such as electrochemical reactions and the limitation of low ionic strength fluids. The three major mechanisms of ACEK, that is, dielectrophoresis, AC electro-osmosis and AC electrothermal effect, provide versatility and flexibility to interface with many current methods and technologies in multiple biological, chemical and physical disciplines. This paper gives an overview of ACEK and its applications, with an emphasis on fluid manipulation by electric fields.
Inspec keywords: lab-on-a-chip; bioMEMS; bioelectric phenomena; microfluidics; electrokinetic effects; osmosis; biological effects of fields; electrophoresis
Other keywords:
Subjects: Electrochemistry and electrophoresis; Bioelectricity; Micromechanical and nanomechanical devices and systems; Film and membrane processes; ion exchange; dialysis; osmosis, electro-osmosis; Biological effects of radiations
References
-
-
1)
- J. Wu . Electrokinetic microfluidics for on-chip bioparticle processing. IEEE Trans. Nanotech , 2 , 84 - 89
-
2)
- K.F. Hoettges , M.B. McDonnel , M.P. Hughes . Use of combined dielectrophoretic/electrohydrodynamic forces for biosensor enhancement. J. Phys. D Appl. Phys. , L101 - L104
-
3)
- E. Cummings , A. Singh . Dielectrophoresis in microchips containing arrays of insulating posts: theoretical and experimental results. Anal. Chem , 18 , 4724 - 4731
-
4)
- M. Lian , N. Islam , J. Wu . AC electrothermal manipulation of conductive fluids and particles for lab-chip applications. IET Nanobiotechnol , 3 , 36 - 43
-
5)
- R. Pethig , I. Karube . (1991) Application of A.C.: electrical fields to the manipulation and characterisation of cells, Automation in Biotechnology.
-
6)
- J. Wu , Y. Ben , D. Battigelli . Long-range AC electrokinetic trapping and detection of bioparticles. Ind. Eng. Chem. Res. , 8 , 2815 - 2822
-
7)
- J. Wu . AC electro-osmotic micropump by asymmetric electrode polarisation. J. Appl. Phys.
-
8)
- J. Wu , Y. Ben , H.-C. Chang . Particle detection by micro- electrical impedance spectroscopy with asymmetric-polarisation AC electro-osmotic trapping. J. Microfluid. Nanofluid , 2 , 161 - 167
-
9)
- A.B.D. Brown , C.G. Smith , A.R. Rennie . Pumping of water with ac electric fields applied to asymmetric pairs of microelectrodes. Phys. Rev. E
-
10)
- A. Ramos , H. Morgan , N.G. Green . AC electrokinetics: a review of forces in microelectrode structures. J. Phys. D: Appl. Phys. , 2338 - 2353
-
11)
- N.G. Green , A. Ramos , A. Gonzalez , H. Morgan , A. Castellanos . Fluid flow induced by nonuniform ac electric fields in electrolytes on microelectrodes. III. Observation of streamlines and numerical simulation. Phys. Rev. E
-
12)
- J.P. Urbanski , T. Thorsen , J.A. Levitan , M.Z. Bazant . Fast AC electro-osmotic pumps with non-planar electrodes. Appl. Phys. Lett.
-
13)
- N.G. Green , A. Ramos , A. Gonzalez , A. Castellanos , H. Morgan . Electrothermally induced fluid flow on microelectrodes. J. Electrostat. , 71 - 87
-
14)
- M.R. Brown , C.D. Meinhart . AC electro-osmotic flow in a DNA concentrator. J. Microfluid. Nanofluid , 513 - 523
-
15)
- D. Lastochkin , R. Zhou , P. Wang . Electrokinetic micorpump and micromixer design based on ac Faradaic polarisation. J. Appl. Phys , 31 , 1730 - 1733
-
16)
- Wu, J., Islam, N., Lian, M.: `High sensitivity particle detection by biased AC electro-osmotic trapping on cantilever', 19thIEEE Int Conf. Micro Electro Mechanical Systems MEMS, 22–26 January 2006, Istanbul, Turkey, p. 566–569.
-
17)
- Wu, J., Islam, N., Lian, M.: `High sensitivity particle detection by biased AC electro-osmotic trapping on cantilever', 19thIEEE Int Conf. Micro Electro Mechanical Systems (MEMS 2006), 22–26 January 2006, Istanbul, Turkey, p. 566–569.
-
18)
- M. Sigurdson , D.Z. Wang , C.D. Meinhart . Electrothermal stirring for heterogeneous immunoassays. Lab Chip , 1366 - 1373
-
19)
- M.Z. Bazant , Y. Ben . Theoretical prediction of fast 3D AC electro-osmotic pumps. Lab Chip , 1455 - 1461
-
20)
- J.S. Newman . (1973) Electrochemical systems.
-
21)
- P.R.C. Gascoyne , J.V. Vykoukal . Dielectrophoresis-based sample handling in general-purpose programmable diagnostic instruments. Proc. IEEE , 22 - 42
-
22)
- Ben, Y.: `Nonlinear electrokinetic phenomena in microfluidic devices', 2004, PhD, University of Notre Dame.
-
23)
- M. Lian , N. Islam , J. Wu . Particle line assembly/patterning by microfluidic AC electro-osmosis. J. Phys. Conf. Ser. , 589 - 594
-
24)
- A. Ramos , H. Morgan , N.G. Green , A. Gonzàlez , A. Castellanos . Pumping of liquids with traveling-wave electroosmosis. J. Appl. Phys.
-
25)
- Wong, P.K., Chen, C.-Y., Wang, T.-H.: `An AC Electro-osmotic Processor for Biomolecules', TRANSDUCERS' 03, 8–12 June 2003, p. 20–23.
-
26)
- H.A. Pohl . (1978) Dielectrophoresis.
-
27)
- N. Green , A. Ramos , A. González . Electric field induced fluid flow on microelectrodes: the effect of illumination. J. Phys. D: Appl. Phys. , L13 - L17
-
28)
- V. Studer , A. Pepin , Y. Chen . An integrated AC electrokinetic pump in a microfluidic loop for fast and tunable flow control. Analyst , 944 - 949
-
29)
- N. Islam , M. Lian , J. Wu . Enhancing cantilever capability with Integrated AC Electrokinetic Trapping Mechanism. J. Microfluid. Nanofluid , 3 , 369 - 375
-
30)
- N.G. Green , A. Ramos , A. Gonzalez , H. Morgan , A. Castellanos . Fluid flow induced by nonuniform ac electric fields in electrolytes on microelectrodes. I. Experimental measurements. Phys. Rev. E , 4011 - 4018
-
31)
- G. Fuhr , T. Schnelle , B. Wagner . Travelling wave-driven microfabricated electrohydrodynamic pumps for liquids. J. Micromech. Microeng , 217 - 226
-
32)
- K.-L. Wang , T.B. Jones , A. Raisanen . Dynamic control of DEP actuation and droplet dispensing. J. Micromech. Microeng , 76 - 80
-
33)
- J. Wu , M. Lian , K. Yang . Micropumping of biofluids by AC electrothermal effects. Appl. Phys. Lett.
-
34)
- H.A. Pohl . Some effects of nonuniform fields on dielectrics. J. Appl. Phys. , 8 , 1182 - 1188
-
35)
- T.M. Squires , M.Z. Bazant . Induced-charge Electro-osmosis. J. Fluid Mech , 217 - 252
-
36)
- A. Ramos , A. Gonzalez , A. Castellanos . Pumping of liquids with AC voltages applied to asymmetric pairs of microelectrodes. Phys. Rev. E
-
37)
- R. Zhou , P. Wang , H.-C. Chang . Bacteria capture, concentration and detection by AC dielectrophoresis and self-assembly of dispersed single-wall carbon nanotubes. Electrophoresis
-
38)
- K.H. Bhatt , S. Grego , O.D. Velev . An AC electrokinetic technique for collection and concentration of particles and cells on patterned electrodes. Langmuir , 6603 - 6612
-
39)
- S. Banerjee , B.E. White , L. Huang . Precise positioning of single-walled carbon nanotubes by ac dielectrophoresis. J. Vac. Sci. Technol , 6 , 3173 - 3178
-
40)
- R. Pethig , P. Somasundaran . (2006) Dielectrophoresis of Biological Cells, Encyclopedia of surface and colloid science.
-
41)
- A. Castellanos , A. Ramos , A. Gonzalez . Electrohydrodynamics and dielectrophoresis in microsystem: scaling laws. J. Phys. D Appl. Phys , 2584 - 2597
-
42)
- A. Gonzalez , A. Ramos , H. Morgan , N. Green , A. Castellanos . Electrothermal flows generated by alternating and rotating electric fields in Microsystems. J. Fluid Mech. , 415 - 433
-
1)