access icon free Synthesis of magnetic, macro/mesoporous bioactive glasses based on coral skeleton for bone tissue engineering

The magnetic and macro/mesoporous bioactive glasses scaffolds are synthesised successfully by the combination of coral and P123 as co-templates through an evaporation-induced self-assembly process. The prepared material can induce the precipitation of hydroxyapatite layers on their surface in SBF only within 12 h. At the same time, the material exhibited excellent super-paramagnetic and mechanical property. Furthermore, the biocompatible assessment confirmed that the obtained material presented the good biocompatibility and the enhanced adherence of HeLa cells. Herein, the novel materials are expected to have potential application for bone tissue engineering.

Inspec keywords: porous materials; precipitation; glass; superparamagnetism; self-assembly; bone; tissue engineering; biomedical materials

Other keywords: hydroxyapatite layers; HeLa cells; superparamagnetic property; biocompatible assessment; bone tissue engineering; evaporation-induced self-assembly process; P123; time 12 h; synthesis; precipitation; magnetic macroporous bioactive glasses; coral skeleton; bioactive glass scaffolds; SBF surface; magnetic mesoporous bioactive glasses; adherence

Subjects: Biological engineering and techniques; Biomedical materials; Precipitation and segregation

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http://iet.metastore.ingenta.com/content/journals/10.1049/iet-nbt.2013.0056
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