access icon free Confocal laser feedback microscopy for in-depth imaging applications

We propose confocal laser feedback microscopy for in-depth imaging of highly scattering samples. This technique provides a compact configuration for microscopy in reflectance mode; it is based on laser feedback interferometry which is a sensing technique where the laser acts as both transmitter and receiver of the beam. Operating at 850 nm, it offers an ideal platform for non-invasive and in vivo imaging of soft biological tissues. To explore the technique, the authors performed microscopic imaging of micro-glass-spheres (with diameter sizes of 10–20 µm) deep within an agar gel sample, at depth of 0.43 mm from the surface. Experimental results show the feasibility of a compact, low-cost, and simple laser-scanning microscope with possible biomedical imaging applications.

Inspec keywords: biomedical optical imaging; laser applications in medicine; biological tissues; laser feedback; optical microscopy

Other keywords: confocal laser feedback microscopy; transmitter; biomedical imaging applications; soft biological tissues; microglass-spheres; laser feedback interferometry; laser-scanning microscopy; receiver; in vivo imaging; agar gel sample; in-depth imaging applications; high-scattering samples; microscopic imaging

Subjects: Optical and laser radiation (biomedical imaging/measurement); Optical and laser radiation (medical uses); Patient diagnostic methods and instrumentation; Biological and medical applications of lasers

References

    1. 1)
    2. 2)
    3. 3)
    4. 4)
    5. 5)
      • 17. Tan, Y., Wang, W., Xu, C., et al: ‘Laser confocal feedback tomography and nano-step height measurement’, Sci. Rep., 2013, 3, pp. 17.
    6. 6)
    7. 7)
    8. 8)
    9. 9)
    10. 10)
    11. 11)
    12. 12)
    13. 13)
    14. 14)
    15. 15)
    16. 16)
    17. 17)
    18. 18)
http://iet.metastore.ingenta.com/content/journals/10.1049/el.2017.4333
Loading

Related content

content/journals/10.1049/el.2017.4333
pub_keyword,iet_inspecKeyword,pub_concept
6
6
Loading
Correspondence
This article has following corresponding article(s):
new techniques for biological tissue imaging