RT Journal Article
A1 J. Smith
AD Flexible Electronics and Display Center, Arizona State University, Tempe, AZ 85284, USA
A1 A. Shah
AD Ira A. Fulton School of Engineering, Arizona State University, Tempe, AZ 85281, USA
A1 Y.K. Lee
AD Flexible Electronics and Display Center, Arizona State University, Tempe, AZ 85284, USA
A1 B. O'Brien
AD Flexible Electronics and Display Center, Arizona State University, Tempe, AZ 85284, USA
A1 D. Kullman
AD Ira A. Fulton School of Engineering, Arizona State University, Tempe, AZ 85281, USA
A1 A. Sridharan
AD Ira A. Fulton School of Engineering, Arizona State University, Tempe, AZ 85281, USA
A1 J. Muthuswamy
AD Ira A. Fulton School of Engineering, Arizona State University, Tempe, AZ 85281, USA
A1 J. Blain Christen
AD Ira A. Fulton School of Engineering, Arizona State University, Tempe, AZ 85281, USA

PB iet
T1 Optogenetic neurostimulation of auricular vagus using flexible OLED display technology to treat chronic inflammatory disease and mental health disorders
JN Electronics Letters
VO 52
IS 11
SP 900
OP 902
AB The viability of a new biophotonic alternative to conventional prescription-drug-based treatments is explored for inflammatory disease and mental health disorders using a non-invasive drug-free optogenetics-based therapy to treat patients by optically stimulating selected afferent branches of the auricular vagus nerve transcutaneously via the outer ear using a high-resolution, addressable array of organic light emitting diodes (OLED) manufactured on a flexible plastic substrate. Preliminary analysis and optical measurements indicate that our 620 nm flexible red OLED display technology is bright enough to induce therapeutic optical stimulation in optogenetically modified neural tissue.
K1 therapeutic optical stimulation
K1 conventional prescription-drug-based treatments
K1 optically stimulating selected afferent branches
K1 optogenetically modified neural tissue
K1 auricular vagus
K1 chronic inflammatory disease
K1 flexible plastic substrate
K1 auricular vagus nerve
K1 high-resolution addressable array
K1 flexible red OLED display technology
K1 outer ear
K1 mental health disorders
K1 optogenetic neurostimulation
K1 biophotonic
K1 organic light emitting diodes
K1 noninvasive drug-free optogenetics-based therapy
DO https://doi.org/10.1049/el.2015.3450
UL https://digital-library.theiet.org/;jsessionid=225ketofuetco.x-iet-live-01content/journals/10.1049/el.2015.3450
LA English
SN 0013-5194
YR 2016
OL EN