In this paper, the electron-gating model to experimental data wherever possible and to account for any differences between the model and the experimental data. A primary experimental link is the Hodgkin-Huxley equations. A detailed study was made to understand the significance of the coefficients and sensitivity factors in terms of the electron-gating model. The amino acid sequence data for the squid giant axon for sodium and potassium ion channels and the sequence data for Shaker B. The experimental data for gating current and gating current time constants was described. Experimental data for electron tunneling across proteins and the α-helix in particular. Experimental determination of the NH3 inversion frequencies. The measured frequencies narrow the range of possible parameter values.

Chapter Contents:

• 6.1 Electron gating model equations
• 6.2 Finite-range rate constants
• 6.3 Open-channel probability range and time constant
• 6.4 Rate curves using voltage-sensitive amplification

Inspec keywords: neurophysiology; potassium; sodium; bioelectric phenomena; proteins; sensitivity; molecular biophysics; tunnelling; molecular configurations

Other keywords: Shaker B; potassium ion channels; proteins; Hodgkin-Huxley equations; sodium ion channels; sensitivity factors; amino acid sequence data; α-helix; gating current time constants; squid giant axon; electron-gating model; electron tunneling; NH₃ inversion frequency

Subjects: Bioelectricity; Electrical activity in neurophysiological processes; Biomolecular structure, configuration, conformation, and active sites; Macromolecular constitution (chains and sequences)