Introduction
The quantum-mechanical approach to channel gating described in this book is based on single-electron tunneling across arginine and lysine residues of the S4 transmembrane protein segment. Models for controlling the gating of ion channels by electrons have most likely been considered by other researchers; however, there is a problem - an electron gating model requires a mechanism for amplification in order to match the experimental data for ion channel voltage sensitivity. Amplification based on the inversion of NH3, addresses this sensitivity problem.
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Introduction, Page 1 of 2
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