Advanced lateral flow technology for point-of-care and field-based applications

Advanced lateral flow technology for point-of-care and field-based applications

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In this chapter, the key components of a lateral-flow system will be discussed and key advances described that facilitate higher performance in field-based applications in any market space, from veterinary infectious disease testing to hormone and biomarker testing in animals and equally to human diagnostic, environmental, and biodefense applications of the technology. Some key principles of designing these devices for ease of use in field environments using user-centric design principles will also be discussed.

Chapter Contents:

  • 3.1 Introduction
  • 3.1.1 Advantages of lateral-flow assay systems
  • 3.1.2 The S-curve and lateral flow
  • 3.2 Lateral-flow assays from first principles: key elements of a high performance lateral-flow assay system
  • 3.2.1 Lateral-flow assay architecture and formats - a brief introduction
  • 3.2.2 Device design
  • Sample collection and handling
  • Recognition and signal generation
  • Fluorescence
  • Reader systems in lateral flow
  • 3.2.3 User-centered design of devices for field-based applications
  • Sample preparation devices
  • Cassette design
  • Arraying in lateral flow formats
  • 3.3 Conclusion
  • Reference

Inspec keywords: patient diagnosis; veterinary medicine; diseases; biomedical equipment

Other keywords: biomarker testing; lateral-flow system; human diagnostic applications; field environments; field-based applications; biodefense applications; hormone testing; veterinary infectious disease testing; environmental applications

Subjects: Biomedical measurement and imaging; Patient diagnostic methods and instrumentation

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