The adoption of biosensor systems in the management of animal care, either at the farm or home is not new. Sensor approaches have been developed since the early 1990s, in parallel with the emergence of automated processes, such as automated milking systems in dairy farming aimed to reduce labor requirements and associated costs. On a different level, customized portable blood glucose meters (PBGM) for monitoring diabetic pets have been commercially available for more than 15 years. Nowadays, a rapid expansion in the number of point-of-care (POC) systems for veterinary science is observed, the scope of which exceeds by far the respective applications for human medicine. In the present chapter, the progress in this continuously evolving field during the last 5 years is briefly reviewed.