Chapter Contents:

• 11.1 Introduction
• 11.2 Data
• 11.2.1 EHR data
• 11.2.2 Genomic data
• 11.3 EVT applied to longitudinal data
• 11.3.1 Classical EVT
• 11.3.2 EVT from a point process perspective
• 11.3.3 Practicalities
• 11.3.4 Application of EVT models to healthcare
• 11.3.5 Advanced topics
• 11.3.6 Conclusions on EVT
• 11.4 Patient clustering
• 11.4.1 Clustering overview
• 11.4.2 Modelling choices applicable to chronic disease applications
• 11.4.3 Clustering extensions
• 11.4.4 Practical considerations in unsupervised clustering
• 11.4.5 Clustering conclusions
• 11.5 Conclusion
• References